当前位置:首页 > 产品中心 > / Primary Antibodies / ALK (phospho-Tyr1078) rabbit pAb
产品分类
CLASSIFICATION详细介绍
Rabbit
WB
Human
WB 1:1000-2000
-20°C/1 year
This antibody detects endogenous levels of Human ALK (phospho-Tyr1078)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Synthesized phosho peptide around human ALK (Tyr1078)
Q9UM73
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Polyclonal
IgG
anaplastic lymphoma receptor tyrosine kinase(ALK) Homo sapiens This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome
ALK, ALK (Tyr1078)
1 mg/ml
Product | Reactivity | Applications | Conjugation | Catalog | Images |
---|
产品咨询
公司地址:上海市浦东新区
公司邮箱:bestbio@163.com
公司传真:
免费销售热线
1722797799微信二维码
网站二维码
微信