ALK (phospho-Tyr1278/1282/1283) rabbit pAb

简要描述：

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更新时间：2024-05-16
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CLASSIFICATION

Primary Antibodies

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详细介绍

Source

Rabbit
Applications

WB
Reactivity

Human
Dilution

WB 1:1000-2000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of Human ALK (phospho-Tyr1278 or 1282 or 1283)
Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Immunogen

Synthesized phosho peptide around human ALK (Tyr1278 and 1282 and 1283)
Uniprot No

Q9UM73
Alternative names

ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

anaplastic lymphoma receptor tyrosine kinase(ALK) Homo sapiens This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome
Other

ALK, ALK (Tyr1278/1282/1283)
Concentration

1 mg/ml

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ALK (phospho-Tyr1278/1282/1283) rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Concentration

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