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Adrenocorticotropin(ACTH) rabbit pAb

简要描述:SourceRabbitApplicationsIHC

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  • 厂商性质:生产厂家
  • 更新时间:2025-03-17
  • 访  问  量:127

详细介绍

  • Source

    Rabbit

  • Applications

    IHC,WB

  • Reactivity

    Human, Mouse, Rat

  • Dilution

    IHC 1:50-200, WB 1:500-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of human Adrenocorticotropin(ACTH)

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized peptide derived from human Adrenocorticotropin(ACTH)

  • Uniprot No

    P01189

  • Alternative names

    Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin]

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    proopiomelanocortin(POMC) Homo sapiens This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. The

  • Other

    POMC, Adrenocorticotropin(ACTH) ; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH); Beta-endorphin; Met-enkephalin], Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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