Caspase-10 (p23/17, Cleaved-Val220) Antibody

简要描述：SourceRabbitApplicationsWB

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更新时间：2024-11-27
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CLASSIFICATION

Primary Antibodies

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详细介绍

Source

Rabbit
Applications

WB, ELISA
Reactivity

Human, Mouse, Rat
Dilution

WB 1:500-2000, ELISA(peptide)1:5000-20000
Storage

-20°C/1 year
Specificity

This antibody detects endogenous levels of human Caspase 10 (p23/17, Cleaved-Val220)
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Synthesized peptide derived from human Caspase 10 (p23/17, Cleaved-Val220)
Uniprot No

Q92851
Alternative names

Caspase-10 (CASP-10) (EC 3.4.22.63) (Apoptotic protease Mch-4) (FAS-associated death domain protein interleukin-1B-converting enzyme 2) (FLICE2) (ICE-like apoptotic protease 4) [Cleaved into: Caspase-10 subunit p23/17; Caspase-10 subunit p12]
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

caspase 10(CASP10) Homo sapiens This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],
Other

CASP10 MCH4, Caspase 10 (p23/17, Cleaved-Val220)
Concentration

1 mg/ml

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Caspase-10 (p23/17, Cleaved-Val220) Antibody

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Concentration

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