CD137L rabbit pAb

简要描述：SourceRabbitApplicationsWB,IF,ELISAReactivityHumanDilutionWB:1:500-1:2000

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更新时间：2024-05-16
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CLASSIFICATION

Primary Antibodies

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详细介绍

Source

Rabbit
Applications

WB,IF,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

CD137L Polyclonal Antibody detects endogenous levels of CD137L protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human TNFSF9. AA range:31-80
Uniprot No

P41273
Alternative names

TNFSF9; Tumor necrosis factor ligａnd superfamily member 9; 4-1BB ligand; 4-1BBL
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

tumor necrosis factor superfamily member 9(TNFSF9) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligａnd family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligａnd for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligａnd encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided b
Other

TNFSF9, Tumor necrosis factor ligａnd superfamily member 9
Mol.Wt (Da)

26625
Concentration

1 mg/ml

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CD137L rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

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