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CaMK2 (Phospho-Thr286) Antibody

简要描述:SourceRabbitApplicationsWB

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  • 厂商性质:生产厂家
  • 更新时间:2024-05-16
  • 访  问  量:68

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详细介绍

  • Source

    Rabbit

  • Applications

    WB, ELISA

  • Reactivity

    Human, Mouse, Rat

  • Dilution

    WB 1:500-2000, ELISA(peptide)1:5000-20000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous pospho levels of human CaMK2 (Phospho-Thr286)

  • Source/Purification

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)

  • Uniprot No

    Q9UQM7/Q13557

  • Alternative names

    Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    calcium/calmodulin dependent protein kinase II alpha(CAMK2A) Homo sapiens The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

  • Other

    CAMK2D CAMKD, CaMK2 (Phospho-Thr286)

  • Concentration

    1 mg/ml

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