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Rabbit
WB,ELISA
Human
WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
-20°C/1 year
CD30-L Polyclonal Antibody detects endogenous levels of CD30-L protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
The antiserum was produced against synthesized peptide derived from the Internal region of human TNFSF8. AA range:131-180
P32971
TNFSF8; CD30L; CD30LG; Tumor necrosis factor ligand superfamily member 8; CD30 ligand; CD30-L; CD153
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Polyclonal
IgG
tumor necrosis factor superfamily member 8(TNFSF8) Homo sapiens The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
TNFSF8, Tumor necrosis factor ligand superfamily member 8
26017
1 mg/ml
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