BRCA1 rabbit pAb

简要描述：SourceRabbitApplicationsIHC,ELISAReactivityHumanDilutionIHC:1:100-1:300

产品型号：
厂商性质：生产厂家
更新时间：2025-07-02
访问量：21

产品咨询联系我们

产品分类

CLASSIFICATION

Primary Antibodies

查看全部产品

相关文章ARTICLES

查看全部

详细介绍

Source

Rabbit
Applications

IHC,ELISA
Reactivity

Human
Dilution

IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

BRCA1 Polyclonal Antibody detects endogenous levels of BRCA1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human BRCA1. AA range:955-1004
Uniprot No

P38398
Alternative names

BRCA1; RNF53; Breast cancer type 1 susceptibility protein; RING finger protein 53
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

BRCA1, DNA repair associated(BRCA1) Homo sapiens This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript varian
Other

BRCA1, Breast cancer type 1 susceptibility protein
Mol.Wt (Da)

207721
Concentration

1 mg/ml

Product	Reactivity	Applications	Conjugation	Catalog	Images

产品咨询

上一篇：BRCA2 (phospho Ser3291) rabbit pAb
下一篇：Brm rabbit pAb

BRCA1 rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

留言框

产品：

您的单位：

您的姓名：

联系电话：

常用邮箱：

省份：

详细地址：

补充说明：

验证码：