BARD1 rabbit pAb

简要描述：SourceRabbitApplicationsWB,IHC,ELISAReactivityHumanDilutionWB:1:500-1:2000

产品型号：
厂商性质：生产厂家
更新时间：2025-06-28
访问量：19

产品咨询联系我们

产品分类

CLASSIFICATION

Primary Antibodies

查看全部产品

相关文章ARTICLES

查看全部

详细介绍

Source

Rabbit
Applications

WB,IHC,ELISA
Reactivity

Human
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

BARD1 Polyclonal Antibody detects endogenous levels of BARD1 protein.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human BARD1. AA range:1-50
Uniprot No

Q99728
Alternative names

BARD1; BRCA1-associated RING domain protein 1; BARD-1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

BRCA1 associated RING domain 1(BARD1) Homo sapiens This gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gen
Other

BARD1, BRCA1-associated RING domain protein 1
Mol.Wt (Da)

86648
Concentration

1 mg/ml

Product	Reactivity	Applications	Conjugation	Catalog	Images

产品咨询

上一篇：Bcl-2 rabbit pAb3
下一篇：BAMBI rabbit pAb

BARD1 rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

留言框

产品：

您的单位：

您的姓名：

联系电话：

常用邮箱：

省份：

详细地址：

补充说明：

验证码：