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AVP Receptor V2 rabbit pAb2

简要描述:SourceRabbitApplicationsWB,IF,ELISAReactivityHumanDilutionWB:1:500-1:2000

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  • 厂商性质:生产厂家
  • 更新时间:2025-06-27
  • 访  问  量:15

详细介绍

  • Source

    Rabbit

  • Applications

    WB,IF,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    AVP Receptor V2 Polyclonal Antibody detects endogenous levels of AVP Receptor V2 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human AVPR2. AA range:72-121

  • Uniprot No

    P30518

  • Alternative names

    AVPR2; ADHR; DIR; DIR3; V2R; Vasopressin V2 receptor; V2R; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    arginine vasopressin receptor 2(AVPR2) Homo sapiens This gene encodes the vasopressin receptor, type 2, also known as the V2 receptor, which belongs to the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily, and couples to Gs thus stimulating adenylate cyclase. The subfamily that includes the V2 receptor, the V1a and V1b vasopressin receptors, the oxytocin receptor, and isotocin and mesotocin receptors in non-mammals, is well conserved, though several members signal via other G proteins. All bind similar cyclic nonapeptide hormones. The V2 receptor is expressed in the kidney tubule, predominantly in the distal convoluted tubule and collecting ducts, where its primary property is to respond to the pituitary hormone arginine vasopressin (AVP) by stimulating mechanisms that concentrate the urine and maintain water homeostasis in the organism. When the function of this gene is lost, the disease Nephrogenic Diabetes Insipidus

  • Other

    AVPR2, Vasopressin V2 receptor; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor

  • Mol.Wt (Da)

    40279

  • Concentration

    1 mg/ml

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