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AAK1 rabbit pAb

简要描述:SourceRabbitApplicationsWB,IHC,IF,ELISAReactivityHuman,Mouse,Rat,MonkeyDilutionWB:1:500-1:2000

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  • 厂商性质:生产厂家
  • 更新时间:2025-01-13
  • 访  问  量:130

详细介绍

  • Source

    Rabbit

  • Applications

    WB,IHC,IF,ELISA

  • Reactivity

    Human,Mouse,Rat,Monkey

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    AAK1 Polyclonal Antibody detects endogenous levels of AAK1 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human AAK1. AA range:271-320

  • Uniprot No

    Q2M2I8

  • Alternative names

    AAK1; KIAA1048; AP2-associated protein kinase 1; Adaptor-associated kinase 1

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    AP2 associated kinase 1(AAK1) Homo sapiens Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

  • Other

    AAK1, AP2-associated protein kinase 1

  • Mol.Wt (Da)

    93578

  • Concentration

    1 mg/ml

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