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Adducin α/β (phospho Ser726/713) rabbit pAb

简要描述:SourceRabbitApplicationsWB,IHC,IF,ELISAReactivityHuman,Mouse,RatDilutionWB:1:500-1:2000

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  • 更新时间:2024-05-16
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详细介绍

  • Source

    Rabbit

  • Applications

    WB,IHC,IF,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Adducin α/β (S726/713) Polyclonal Antibody detects endogenous levels of Adducin α/β protein only when phosphorylated at S726/713.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human ADD1 around the phosphorylation site of Ser726. AA range:688-737

  • Uniprot No

    P35611/P35612

  • Alternative names

    ADD1; ADDA; Alpha-adducin; Erythrocyte adducin subunit alpha; ADD2; ADDB; Beta-adducin; Erythrocyte adducin subunit beta

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    adducin 1(ADD1) Homo sapiens Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008],

  • Other

    ADD1/ADD2, Alpha-adducin/Beta-adducin; Alpha-adducin; Erythrocyte adducin subunit alpha; Erythrocyte adducin subunit beta

  • Mol.Wt (Da)

    80955

  • Concentration

    1 mg/ml

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