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Calpain 10 rabbit pAb

简要描述:SourceRabbitApplicationsWB,ELISAReactivityHumanDilutionWB:1:500-1:2000

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  • 更新时间:2024-05-16
  • 访  问  量:49

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详细介绍

  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Calpain 10 Polyclonal Antibody detects endogenous levels of Calpain 10 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from the N-terminal region of human Calpain 10.

  • Uniprot No

    Q9HC96

  • Alternative names

    CAPN10; KIAA1845; Calpain-10; Calcium-activated neutral proteinase 10; CANP 10

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    calpain 10(CAPN10) Homo sapiens Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq,

  • Other

    CAPN10, Calpain-10

  • Mol.Wt (Da)

    74938

  • Concentration

    1 mg/ml

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