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CARD11 (phospho-Ser652) rabbit pAb

简要描述:SourceRabbitApplicationsWBReactivityHuman

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  • 厂商性质:生产厂家
  • 更新时间:2024-11-27
  • 访  问  量:75

详细介绍

  • Source

    Rabbit

  • Applications

    WB

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB 1:1000-2000

  • Storage

    -20°C/1 year

  • Specificity

    This antibody detects endogenous levels of Human Mouse Rat CARD11 (phospho-Ser652)

  • Source/Purification

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

  • Immunogen

    Synthesized phosho peptide around human CARD11 (Ser652)

  • Uniprot No

    Q9BXL7

  • Alternative names

    Caspase recruitment domain-containing protein 11 (CARD-containing MAGUK protein 1) (Carma 1)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    caspase recruitment domain family member 11(CARD11) Homo sapiens The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],

  • Other

    CARD11 CARMA1, CARD11 (Ser652)

  • Concentration

    1 mg/ml

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