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CARD 11 rabbit pAb

简要描述:SourceRabbitApplicationsWB,IHC,IF,ELISAReactivityHuman,MouseDilutionWB:1:500-1:2000

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  • 更新时间:2024-05-16
  • 访  问  量:49

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详细介绍

  • Source

    Rabbit

  • Applications

    WB,IHC,IF,ELISA

  • Reactivity

    Human,Mouse

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CARD 11 Polyclonal Antibody detects endogenous levels of CARD 11 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human CARD11. AA range:10-59

  • Uniprot No

    Q9BXL7

  • Alternative names

    CARD11; CARMA1; Caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 1; Carma 1

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    caspase recruitment domain family member 11(CARD11) Homo sapiens The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],

  • Other

    CARD11, Caspase recruitment domain-containing protein 11

  • Mol.Wt (Da)

    132658

  • Concentration

    1 mg/ml

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