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Caspase-9 (phospho Ser144) rabbit pAb

简要描述:SourceRabbitApplicationsWB,IHC,ELISAReactivityHumanDilutionWB:1:500-1:2000

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  • 厂商性质:生产厂家
  • 更新时间:2024-11-27
  • 访  问  量:80

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详细介绍

  • Source

    Rabbit

  • Applications

    WB,IHC,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Caspase-9 (S144) Polyclonal Antibody detects endogenous levels of Caspase-9 protein only when phosphorylated at S144.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human Caspase 9 around the phosphorylation site of Ser144. AA range:110-159

  • Uniprot No

    P55211

  • Alternative names

    CASP9; MCH6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    caspase 9(CASP9) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

  • Other

    CASP9, Caspase-9

  • Mol.Wt (Da)

    46281

  • Concentration

    1 mg/ml

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