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CD158a rabbit pAb

简要描述:SourceRabbitApplicationsWB,ELISAReactivityHumanDilutionWB:1:500-1:2000

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  • 更新时间:2024-05-16
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详细介绍

  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB: 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CD158a Polyclonal Antibody detects endogenous levels of CD158a protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from the Internal region of human KIR2DL1. AA range:131-180

  • Uniprot No

    P43626

  • Alternative names

    KIR2DL1; CD158A; NKAT1; Killer cell immunoglobulin-like receptor 2DL1; CD158 antigen-like family member A; MHC class I NK cell receptor; Natural killer-associated transcript 1; NKAT-1; p58 natural killer cell receptor clones CL-42/47.11; p58 NK receptor CL-42/47.11; p58.1 MHC class-I-specific NK receptor; CD158a

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1(KIR2DL1) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the

  • Other

    KIR2DL1, Killer cell immunoglobulin-like receptor 2DL1

  • Mol.Wt (Da)

    38505

  • Concentration

    1 mg/ml

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