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BMPR-IB rabbit pAb

简要描述:SourceRabbitApplicationsIHC

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  • 厂商性质:生产厂家
  • 更新时间:2025-07-02
  • 访  问  量:23

详细介绍

  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human,Mouse

  • Dilution

    IHC 1:50-200, ELISA 1:10000-20000

  • Storage

    -20°C/1 year

  • Specificity

    The antibody detects endogenous BMPR-IB

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthetic peptide from human protein at AA range: 21-70

  • Uniprot No

    O00238

  • Alternative names

    Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    bone morphogenetic protein receptor type 1B(BMPR1B) Homo sapiens This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for thi

  • Other

    BMPR1B, Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)

  • Concentration

    1 mg/ml

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