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Bax (phospho Thr167) rabbit pAb

简要描述:SourceRabbitApplicationsIF,ELISAReactivityHuman,Mouse,RatDilutionIF:1:200-1:1000

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  • 厂商性质:生产厂家
  • 更新时间:2025-07-02
  • 访  问  量:31

详细介绍

  • Source

    Rabbit

  • Applications

    IF,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    IF: 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    Phospho-Bax (T167) Polyclonal Antibody detects endogenous levels of Bax protein only when phosphorylated at T167.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Thr167. AA range:133-182

  • Uniprot No

    Q07812

  • Alternative names

    BAX; BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.

  • Other

    BAX, Apoptosis regulator BAX

  • Mol.Wt (Da)

    21184

  • Concentration

    1 mg/ml

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