ATM mouse mAb(3D3)

简要描述：SourceMouseApplicationsIHCReactivityHuman

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详细介绍

Source

Mouse
Applications

IHC
Reactivity

Human,Rat,Mouse
Dilution

IHC 1:100-200
Storage

-20°C/1 year
Specificity

ATM protein detects endogenous levels of ATM
Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Immunogen

Recombinant Protein of ATM of ATM
Uniprot No

Q13315
Alternative names

ATM
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Monoclonal
Isotype

IgG
Background

ATM serine/threonine kinase(ATM) Homo sapiens The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010],
Other

ATM, ATM
Concentration

1 mg/ml

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