BAI1 rabbit pAb

简要描述：SourceRabbitApplicationsWB,IHCReactivityHuman,Rat,MouseDilutionWB:1:500-1:2000

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更新时间：2025-07-01
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CLASSIFICATION

Primary Antibodies

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详细介绍

Source

Rabbit
Applications

WB,IHC
Reactivity

Human,Rat,Mouse
Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

The antibody detects endogenous BAI1 protein
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

Synthetic Peptide of BAI1
Uniprot No

O14514
Alternative names

Brain-specific angiogenesis inhibitor 1
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

adhesion G protein-coupled receptor B1(ADGRB1) Homo sapiens Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family,
Other

BAI1, Brain-specific angiogenesis inhibitor 1
Concentration

1 mg/ml

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BAI1 rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Concentration

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