Catenin-β (phospho Ser33) rabbit pAb

简要描述：SourceRabbitApplicationsIHC,IF,WB,ELISAReactivityHuman,Mouse,RatDilutionWB1:500-2000IHC:1:100-1:300

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更新时间：2024-11-27
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CLASSIFICATION

Primary Antibodies

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详细介绍

Source

Rabbit
Applications

IHC,IF,WB,ELISA
Reactivity

Human,Mouse,Rat
Dilution

WB 1:500-2000 IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
Storage

-20°C/1 year
Specificity

Phospho-Catenin-β (S33) Polyclonal Antibody detects endogenous levels of Catenin-β protein only when phosphorylated at S33.
Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen

The antiserum was produced against synthesized peptide derived from human Catenin-beta around the phosphorylation site of Ser33. AA range:17-66
Uniprot No

P35222
Alternative names

CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin
Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality

Polyclonal
Isotype

IgG
Background

catenin beta 1(CTNNB1) Homo sapiens The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],
Other

CTNNB1, Catenin beta-1
Mol.Wt (Da)

85497
Concentration

1 mg/ml

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Catenin-β (phospho Ser33) rabbit pAb

Source

Applications

Reactivity

Dilution

Storage

Specificity

Source/Purification

Immunogen

Uniprot No

Alternative names

Form

Clonality

Isotype

Background

Other

Mol.Wt (Da)

Concentration

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