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CD284 rabbit pAb

简要描述:SourceRabbitApplicationsIF,WB,IHC,ELISAReactivityHuman,MouseDilutionIF:1:50-200WB:1:500-1:2000

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  • 更新时间:2024-05-16
  • 访  问  量:62

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详细介绍

  • Source

    Rabbit

  • Applications

    IF,WB,IHC,ELISA

  • Reactivity

    Human,Mouse

  • Dilution

    IF: 1:50-200 WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. ELISA: 1:40000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    CD284 Polyclonal Antibody detects endogenous levels of CD284 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human CD284. AA range:392-441

  • Uniprot No

    O00206

  • Alternative names

    TLR4; Toll-like receptor 4; hToll; CD antigen CD284

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    toll like receptor 4(TLR4) Homo sapiens The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

  • Other

    TLR4, Toll-like receptor 4

  • Mol.Wt (Da)

    95680

  • Concentration

    1 mg/ml

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