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TBP/TATA Binding Protein mouse mAb(1F6)

简要描述:SourceMouseApplicationsIHCReactivityHuman

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  • 更新时间:2024-05-15
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详细介绍

  • Source

    Mouse

  • Applications

    IHC

  • Reactivity

    Human,Rat,Mouse

  • Dilution

    IHC 1:50-200

  • Storage

    -20°C/1 year

  • Specificity

    TBP/TATA Binding Protein protein detects endogenous levels of TBP/TATA Binding Protein

  • Source/Purification

    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

  • Immunogen

    Recombinant Protein of TBP/TATA Binding Protein

  • Uniprot No

    P20226

  • Alternative names

    TBP/TATA Binding Protein

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Monoclonal

  • Background

    TATA-box binding protein(TBP) Homo sapiens Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin

  • Concentration

    1 mg/ml

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